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adx her2 mutation detection kit (amoy diagnostics, xiamen, china)  (Amoy Diagnostics)

 
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    Structured Review

    Amoy Diagnostics adx her2 mutation detection kit (amoy diagnostics, xiamen, china)
    Baseline Characteristics of <t> HER2‐Mutant </t> patients in first‐line treatment.
    Adx Her2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China), supplied by Amoy Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/adx+her2+mutation+detection+kit/human+egfr+gene+mutation+detection+kit/pmc11194746-118-1-6
    Average 90 stars, based on 1 article reviews
    adx her2 mutation detection kit (amoy diagnostics, xiamen, china) - by Bioz Stars, 2026-09
    90/100 stars

    Images

    1) Product Images from "A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations"

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    Journal: Cancer Medicine

    doi: 10.1002/cam4.7335

    Baseline Characteristics of  HER2‐Mutant  patients in first‐line treatment.
    Figure Legend Snippet: Baseline Characteristics of HER2‐Mutant patients in first‐line treatment.

    Techniques Used:

    Kaplan–Meier survival curves of PFS in HER2 mutation. (A) Chemotherapy + ICIs versus chemotherapy; (B) PD‐L1 Negative versus PD‐L1 Positive; (C) chemotherapy + bevacizumab versus chemotherapy; (D) chemotherapy + bevacizumab versus chemotherapy + ICIs; (E) pyrotinib versus chemotherapy; (F) pyrotinib versus chemotherapy + ICIs.
    Figure Legend Snippet: Kaplan–Meier survival curves of PFS in HER2 mutation. (A) Chemotherapy + ICIs versus chemotherapy; (B) PD‐L1 Negative versus PD‐L1 Positive; (C) chemotherapy + bevacizumab versus chemotherapy; (D) chemotherapy + bevacizumab versus chemotherapy + ICIs; (E) pyrotinib versus chemotherapy; (F) pyrotinib versus chemotherapy + ICIs.

    Techniques Used: Mutagenesis

    Clinical and pathological characteristics of  HER2‐mutant  patients treated with pyrotinib after first‐line treatment progression in this study.
    Figure Legend Snippet: Clinical and pathological characteristics of HER2‐mutant patients treated with pyrotinib after first‐line treatment progression in this study.

    Techniques Used:

    HER2‐mutant patients treated with pyrotinib after first‐line treatment progression. (A) Survival benefits of Pyrotinib based on treatment data and line of treatment. (B) Kaplan–Meier survival curves of PFS based on first‐line treatment PFS; (C) univariate analysis; (D) multivariate analysis.
    Figure Legend Snippet: HER2‐mutant patients treated with pyrotinib after first‐line treatment progression. (A) Survival benefits of Pyrotinib based on treatment data and line of treatment. (B) Kaplan–Meier survival curves of PFS based on first‐line treatment PFS; (C) univariate analysis; (D) multivariate analysis.

    Techniques Used: Mutagenesis

    Summary of genomic landscape and clinical features in HER2‐Mutant NSCLC with immunotherapy. (A) Mutation frequency; (B) Kaplan–Meier survival curves of OS; (C) OncoPrint that top 20 gene alterations.
    Figure Legend Snippet: Summary of genomic landscape and clinical features in HER2‐Mutant NSCLC with immunotherapy. (A) Mutation frequency; (B) Kaplan–Meier survival curves of OS; (C) OncoPrint that top 20 gene alterations.

    Techniques Used: Mutagenesis

    Reported retrospective studies on the efficacy of first‐line treatment for advanced NSCLC with  HER2‐Mutant.
    Figure Legend Snippet: Reported retrospective studies on the efficacy of first‐line treatment for advanced NSCLC with HER2‐Mutant.

    Techniques Used: Control

    Related Articles

    Mutagenesis:

    Article Title: Outcomes of Pemetrexed-based chemotherapies in HER2 -mutant lung cancers
    Article Snippet: .. HER2 mutation testing was performed using the method of amplification refractory mutation system(ARMS) by ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China). ..

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations
    Article Snippet: .. In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment. ..

    Article Title: Pyrotinib in <i>HER2</i>-Mutant Advanced Lung Adenocarcinoma After Platinum-Based Chemotherapy: A Multicenter, Open-Label, Single-Arm, Phase II Study
    Article Snippet: Eligible patients were 18-75 years old and had histologically or cytologically confirmed HER2-mutant NSCLC (adenocarcinoma) with unresectable stage IIIB or IV disease according to the seventh edition of the International Association for the Study of Lung Cancer staging system.28 HER2 mutation was tested using an ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) at a central laboratory (WuXi NextCODE, Shanghai, China).

    Article Title: HER2 exon 20 insertions in non-small-cell lung cancer are sensitive to the irreversible pan-HER receptor tyrosine kinase inhibitor pyrotinib
    Article Snippet: .. HER2 mutation was tested using ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) or NGS, and confirmed by DNA direct sequencing if needed. ..

    Article Title: Pyrotinib in <i>HER2</i>-Mutant Advanced Lung Adenocarcinoma After Platinum-Based Chemotherapy: A Multicenter, Open-Label, Single-Arm, Phase II Study
    Article Snippet: RESULTS Between October 20, 2016, and December 10, 2018, 60 patients received pyrotinib monotherapy.. At baseline, 58 (96.7%) were stage IV, and 25 (41.7%) received at least 2 lines of prior chemotherapy.. As of data cutoff on June 20, 2019, IRC-assessed objective response rate was 30.0% (95% CI, 18.8% to 43.2%).

    Amplification:

    Article Title: Outcomes of Pemetrexed-based chemotherapies in HER2 -mutant lung cancers
    Article Snippet: .. HER2 mutation testing was performed using the method of amplification refractory mutation system(ARMS) by ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China). ..

    Biomarker Discovery:

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations
    Article Snippet: .. In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment. ..

    Next-Generation Sequencing:

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations
    Article Snippet: .. In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment. ..

    Article Title: HER2 exon 20 insertions in non-small-cell lung cancer are sensitive to the irreversible pan-HER receptor tyrosine kinase inhibitor pyrotinib
    Article Snippet: .. HER2 mutation was tested using ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) or NGS, and confirmed by DNA direct sequencing if needed. ..

    Sequencing:

    Article Title: HER2 exon 20 insertions in non-small-cell lung cancer are sensitive to the irreversible pan-HER receptor tyrosine kinase inhibitor pyrotinib
    Article Snippet: .. HER2 mutation was tested using ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) or NGS, and confirmed by DNA direct sequencing if needed. ..



    Similar Products

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    Amoy Diagnostics adx her2 mutation detection kit (amoy diagnostics, xiamen, china)
    Baseline Characteristics of <t> HER2‐Mutant </t> patients in first‐line treatment.
    Adx Her2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China), supplied by Amoy Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/adx+her2+mutation+detection+kit/human+egfr+gene+mutation+detection+kit/pmc11194746-118-1-6
    Average 90 stars, based on 1 article reviews
    adx her2 mutation detection kit (amoy diagnostics, xiamen, china) - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    90
    Amoy Diagnostics adx her2 mutation detection kit
    Baseline Characteristics of <t> HER2‐Mutant </t> patients in first‐line treatment.
    Adx Her2 Mutation Detection Kit, supplied by Amoy Diagnostics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/adx+her2+mutation+detection+kit/human+egfr+gene+mutation+detection+kit/pmc11194746-111-31-36
    Average 90 stars, based on 1 article reviews
    adx her2 mutation detection kit - by Bioz Stars, 2026-09
    90/100 stars
      Buy from Supplier

    Image Search Results


    Baseline Characteristics of  HER2‐Mutant  patients in first‐line treatment.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Baseline Characteristics of HER2‐Mutant patients in first‐line treatment.

    Article Snippet: The ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) can detect various HER2 mutation types, including 12‐bp exon 20 insertion, G776 mutations, 9‐bp exon 20 insertion, V777L mutation, and L755p mutation.

    Techniques:

    Kaplan–Meier survival curves of PFS in HER2 mutation. (A) Chemotherapy + ICIs versus chemotherapy; (B) PD‐L1 Negative versus PD‐L1 Positive; (C) chemotherapy + bevacizumab versus chemotherapy; (D) chemotherapy + bevacizumab versus chemotherapy + ICIs; (E) pyrotinib versus chemotherapy; (F) pyrotinib versus chemotherapy + ICIs.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Kaplan–Meier survival curves of PFS in HER2 mutation. (A) Chemotherapy + ICIs versus chemotherapy; (B) PD‐L1 Negative versus PD‐L1 Positive; (C) chemotherapy + bevacizumab versus chemotherapy; (D) chemotherapy + bevacizumab versus chemotherapy + ICIs; (E) pyrotinib versus chemotherapy; (F) pyrotinib versus chemotherapy + ICIs.

    Article Snippet: The ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) can detect various HER2 mutation types, including 12‐bp exon 20 insertion, G776 mutations, 9‐bp exon 20 insertion, V777L mutation, and L755p mutation.

    Techniques: Mutagenesis

    Clinical and pathological characteristics of  HER2‐mutant  patients treated with pyrotinib after first‐line treatment progression in this study.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Clinical and pathological characteristics of HER2‐mutant patients treated with pyrotinib after first‐line treatment progression in this study.

    Article Snippet: The ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) can detect various HER2 mutation types, including 12‐bp exon 20 insertion, G776 mutations, 9‐bp exon 20 insertion, V777L mutation, and L755p mutation.

    Techniques:

    HER2‐mutant patients treated with pyrotinib after first‐line treatment progression. (A) Survival benefits of Pyrotinib based on treatment data and line of treatment. (B) Kaplan–Meier survival curves of PFS based on first‐line treatment PFS; (C) univariate analysis; (D) multivariate analysis.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: HER2‐mutant patients treated with pyrotinib after first‐line treatment progression. (A) Survival benefits of Pyrotinib based on treatment data and line of treatment. (B) Kaplan–Meier survival curves of PFS based on first‐line treatment PFS; (C) univariate analysis; (D) multivariate analysis.

    Article Snippet: The ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) can detect various HER2 mutation types, including 12‐bp exon 20 insertion, G776 mutations, 9‐bp exon 20 insertion, V777L mutation, and L755p mutation.

    Techniques: Mutagenesis

    Summary of genomic landscape and clinical features in HER2‐Mutant NSCLC with immunotherapy. (A) Mutation frequency; (B) Kaplan–Meier survival curves of OS; (C) OncoPrint that top 20 gene alterations.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Summary of genomic landscape and clinical features in HER2‐Mutant NSCLC with immunotherapy. (A) Mutation frequency; (B) Kaplan–Meier survival curves of OS; (C) OncoPrint that top 20 gene alterations.

    Article Snippet: The ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) can detect various HER2 mutation types, including 12‐bp exon 20 insertion, G776 mutations, 9‐bp exon 20 insertion, V777L mutation, and L755p mutation.

    Techniques: Mutagenesis

    Reported retrospective studies on the efficacy of first‐line treatment for advanced NSCLC with  HER2‐Mutant.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Reported retrospective studies on the efficacy of first‐line treatment for advanced NSCLC with HER2‐Mutant.

    Article Snippet: The ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) can detect various HER2 mutation types, including 12‐bp exon 20 insertion, G776 mutations, 9‐bp exon 20 insertion, V777L mutation, and L755p mutation.

    Techniques: Control

    Baseline Characteristics of  HER2‐Mutant  patients in first‐line treatment.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Baseline Characteristics of HER2‐Mutant patients in first‐line treatment.

    Article Snippet: In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment.

    Techniques:

    Kaplan–Meier survival curves of PFS in HER2 mutation. (A) Chemotherapy + ICIs versus chemotherapy; (B) PD‐L1 Negative versus PD‐L1 Positive; (C) chemotherapy + bevacizumab versus chemotherapy; (D) chemotherapy + bevacizumab versus chemotherapy + ICIs; (E) pyrotinib versus chemotherapy; (F) pyrotinib versus chemotherapy + ICIs.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Kaplan–Meier survival curves of PFS in HER2 mutation. (A) Chemotherapy + ICIs versus chemotherapy; (B) PD‐L1 Negative versus PD‐L1 Positive; (C) chemotherapy + bevacizumab versus chemotherapy; (D) chemotherapy + bevacizumab versus chemotherapy + ICIs; (E) pyrotinib versus chemotherapy; (F) pyrotinib versus chemotherapy + ICIs.

    Article Snippet: In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment.

    Techniques: Mutagenesis

    Clinical and pathological characteristics of  HER2‐mutant  patients treated with pyrotinib after first‐line treatment progression in this study.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Clinical and pathological characteristics of HER2‐mutant patients treated with pyrotinib after first‐line treatment progression in this study.

    Article Snippet: In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment.

    Techniques:

    HER2‐mutant patients treated with pyrotinib after first‐line treatment progression. (A) Survival benefits of Pyrotinib based on treatment data and line of treatment. (B) Kaplan–Meier survival curves of PFS based on first‐line treatment PFS; (C) univariate analysis; (D) multivariate analysis.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: HER2‐mutant patients treated with pyrotinib after first‐line treatment progression. (A) Survival benefits of Pyrotinib based on treatment data and line of treatment. (B) Kaplan–Meier survival curves of PFS based on first‐line treatment PFS; (C) univariate analysis; (D) multivariate analysis.

    Article Snippet: In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment.

    Techniques: Mutagenesis

    Summary of genomic landscape and clinical features in HER2‐Mutant NSCLC with immunotherapy. (A) Mutation frequency; (B) Kaplan–Meier survival curves of OS; (C) OncoPrint that top 20 gene alterations.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Summary of genomic landscape and clinical features in HER2‐Mutant NSCLC with immunotherapy. (A) Mutation frequency; (B) Kaplan–Meier survival curves of OS; (C) OncoPrint that top 20 gene alterations.

    Article Snippet: In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment.

    Techniques: Mutagenesis

    Reported retrospective studies on the efficacy of first‐line treatment for advanced NSCLC with  HER2‐Mutant.

    Journal: Cancer Medicine

    Article Title: A retrospective study of first‐line therapy and subsequent pyrotinib treatment in advanced lung adenocarcinoma with HER2 mutations

    doi: 10.1002/cam4.7335

    Figure Lengend Snippet: Reported retrospective studies on the efficacy of first‐line treatment for advanced NSCLC with HER2‐Mutant.

    Article Snippet: In the first‐line treatment cohort, the inclusion criteria were as follows: (1) age ≥ 18 years, (2) HER2 mutations detected at the time of initial diagnosis through next‐generation sequencing (NGS) or ADx HER2 Mutation Detection Kit (Amoy Diagnostics, Xiamen, China) in tumor tissue or liquid biopsy samples, (3) without EGFR sensitizing mutations and ALK rearrangements, and (4) receipt of first‐line treatment.

    Techniques: Control